Blanco Ray Gervacio F, Califano Joseph, Messing Barbara, Richmon Jeremy, Liu Jia, Quon Harry, Neuner Geoffrey, Saunders John, Ha Patrick K, Sheth Sheila, Gillison Maura, Fakhry Carole
Department of Otolaryngology - Head and Neck Surgery, Division of Head and Neck Surgery, Johns Hopkins Medicine, Baltimore, Maryland, United States of America ; Milton J. Dance, Jr. Head and Neck Center, Greater Baltimore Medical Center, Baltimore, Maryland, United States of America.
Milton J. Dance, Jr. Head and Neck Center, Greater Baltimore Medical Center, Baltimore, Maryland, United States of America.
PLoS One. 2014 Jan 30;9(1):e87565. doi: 10.1371/journal.pone.0087565. eCollection 2014.
Base of tongue (BOT) is a difficult subsite to examine clinically and radiographically. Yet, anatomic delineation of the primary tumor site, its extension to adjacent sites or across midline, and endophytic vs. exophytic extent are important characteristics for staging and treatment planning. We hypothesized that ultrasound could be used to visualize and describe BOT tumors.
Transcervical ultrasound was performed using a standardized protocol in cases and controls. Cases had suspected or confirmed BOT malignancy. Controls were healthy individuals without known malignancy.
100% of BOT tumors were visualized. On ultrasound BOT tumors were hypoechoic (90.9%) with irregular margins (95.5%). Ultrasound could be used to characterize adjacent site involvement, midline extent, and endophytic extent, and visualize the lingual artery. No tumors were suspected for controls.
Ultrasonography can be used to transcervically visualize BOT tumors and provides clinically relevant characteristics that may not otherwise be appreciable.
舌根(BOT)是临床上和影像学上难以检查的亚部位。然而,原发肿瘤部位的解剖学界定、其向相邻部位或跨越中线的扩展以及内生性与外生性范围是分期和治疗规划的重要特征。我们假设超声可用于可视化和描述舌根肿瘤。
对病例和对照采用标准化方案进行经颈超声检查。病例为疑似或确诊的舌根恶性肿瘤。对照为无已知恶性肿瘤的健康个体。
100%的舌根肿瘤可被可视化。超声检查显示,舌根肿瘤呈低回声(90.9%),边缘不规则(95.5%)。超声可用于确定相邻部位受累情况、中线范围和内生性范围,并可视化舌动脉。对照中未怀疑有肿瘤。
超声检查可用于经颈可视化舌根肿瘤,并提供临床上相关的特征,否则这些特征可能无法被察觉。