Laboratorio de Biomateriais, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Colloids Surf B Biointerfaces. 2014 Mar 1;115:400-5. doi: 10.1016/j.colsurfb.2013.12.027. Epub 2013 Dec 19.
Nanometric hydroxyapatite (HAp) particles were modified with 5 or 10 wt.% tetraethylorthosilicate (TEOS) solutions in order to prepare polydimethylsiloxane/hydroxyapatite (PDMS/HAp) composites. The surface modification of the HAp particles was studied by transmission electron spectroscopy (TEM) and by scanning electron microscopy coupled with energy dispersive spectroscopy (SEM/EDS) equipment. The dispersion state of the modified particles in the PDMS matrix was also assessed by SEM. The composite phase composition was characterized by X-ray diffraction (XRD). The composite thermodynamic parameters of cross-linking were analyzed by differential scanning calorimetry (DSC). TEM micrographs and EDS spectra indicated evidence of silica-coating formation on the surface of modified HAp particles. SEM results showed that the HAp particles formed agglomerates in the PDMS matrix. It was found that the introduction of HAp particles into the PDMS changed the enthalpy of cross-linking and the temperature of the beginning of the cross-linking reaction. EDS results indicated that the surface modification of HAp produced composites showing thermodynamic parameters that were more similar to those of unfilled PDMS.
纳米羟基磷灰石（HAp）颗粒用 5 或 10wt%的正硅酸乙酯（TEOS）溶液进行改性，以制备聚二甲基硅氧烷/羟基磷灰石（PDMS/HAp）复合材料。通过透射电子显微镜（TEM）和扫描电子显微镜结合能谱仪（SEM/EDS）设备研究了 HAp 颗粒的表面改性。SEM 还评估了改性颗粒在 PDMS 基体中的分散状态。通过 X 射线衍射（XRD）对复合材料的相组成进行了表征。通过差示扫描量热法（DSC）分析了复合材料的交联热力学参数。TEM 显微照片和 EDS 图谱表明，改性 HAp 颗粒表面形成了硅涂层。SEM 结果表明，HAp 颗粒在 PDMS 基体中形成了团聚体。研究发现，将 HAp 颗粒引入 PDMS 中会改变交联的焓和交联反应开始的温度。EDS 结果表明，HAp 的表面改性产生了热力学参数更类似于未填充 PDMS 的复合材料。
