Reimann H J, Lewin J, Schmidt U, Ring J, Blümel G
II. Medizinische Klinik u. Poliklinik rechts der Isar der TU München.
Z Hautkr. 1987;62 Suppl 1:45-54.
Various lymphocyte populations, dendritic cells and macrophages contribute to the intake of antigen. The transportation of antigen in the intestinal wall is possible with the help of receptive endocytosis, including extracellular protein in fluid droplets, bacterial and vegetable toxins, as well as certain viruses, which seem to be able to penetrate the cell membrane and enter directly into the cell. Own investigations: After endoscope controlled allergy-irritation of the gastro-intestinal tract, 20 people used in the clinical test showed acute signs of mucosal reaction with inflammation and swelling of the mucous membrane as well as haemorrhagic lesions. A histamine release from the mastcell was proved.
多种淋巴细胞群体、树突状细胞和巨噬细胞参与抗原摄取。在受体介导的内吞作用的帮助下,抗原可在肠壁内运输,包括液滴中的细胞外蛋白、细菌和植物毒素,以及某些似乎能够穿透细胞膜并直接进入细胞的病毒。自身研究:在内窥镜控制下对胃肠道进行过敏刺激后,参与临床试验的20人出现了黏膜反应的急性症状,包括黏膜炎症、肿胀以及出血性病变。已证实肥大细胞释放组胺。