重症疟疾的临床特征：来自印度北部一家三级医疗中心的研究。
Clinical profile of severe malaria: study from a tertiary care center in north India.
作者信息
Nandwani Shafali, Pande Apurva, Saluja Mahip
机构信息
Subharti Institute of Medical Sciences, Meerut, Uttar Pradesh India.
出版信息
J Parasit Dis. 2014 Mar;38(1):11-5. doi: 10.1007/s12639-012-0208-y. Epub 2012 Nov 21.
One hundred and sixty patients having clinical features of severe malaria reported during monsoon season-August-October 2010 at this tertiary care center of north India. Of these 110 (68.75 %) had Plasmodium vivax infection, 30 (18.75 %) were infected with P. falciparum and 20 (12.5 %) had co-infection due to P. vivax and P. falciparum. The diagnosis was made using Rapid Card Test and was confirmed by peripheral smear examination of thick and thin films. Several complications such as acute kidney injury, jaundice, severe anemia, metabolic acidosis, shock, hyperpyrexia, hypoglycemia, generalized tonic-clonic convulsions etc. were found to be more prevalent in patients with P. vivax infection. These symptoms were until recently known to be associated with falciparum malaria.
2010年8月至10月季风季节期间，在印度北部这家三级医疗中心报告了160例具有严重疟疾临床特征的患者。其中，110例（68.75%）感染间日疟原虫，30例（18.75%）感染恶性疟原虫，20例（12.5%）同时感染间日疟原虫和恶性疟原虫。诊断采用快速卡片检测，并通过厚血膜和薄血膜外周涂片检查进行确认。发现间日疟原虫感染患者中，急性肾损伤、黄疸、严重贫血、代谢性酸中毒、休克、高热、低血糖、全身强直阵挛性惊厥等多种并发症更为普遍。直到最近，这些症状还被认为与恶性疟疾有关。
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