Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, Jena, Thuringia 07740, Germany.
AIDS Res Ther. 2014 Feb 7;11(1):11. doi: 10.1186/1742-6405-11-11.
Long and short term side effects of antiretroviral drugs are not fully understood yet. Here a case of reversible blood count changes following post exposure prophylaxis with tenofovir/emtricitabin and lopinavir/ritonavir is reported. We propose that antiretroviral drugs used in post exposure prophylaxis may have a significant impact on hematopoiesis.
抗逆转录病毒药物的长期和短期副作用尚未完全了解。在此报告了一例在接触后预防中使用替诺福韦/恩曲他滨和洛匹那韦/利托那韦后出现可逆的血细胞计数变化的病例。我们提出,接触后预防中使用的抗逆转录病毒药物可能对造血有重大影响。