Abe S, Makimura S, Kawakami Y, Yamamoto H, Nojima T, Inoue K
First Department of Medicine, Faculty of Medicine, Hokkaido University.
Hokkaido Igaku Zasshi. 1987 Dec;62(6):907-12.
The cytomorphologic features of voided urine specimens from two patients with antiallergic drug (Tranilast)-induced eosinophilic cystitis are described. The urothelial cells tend to occur in clusters and are of variable size. The remarkable vacuolization is observed in the cytoplasm. The markedly vacuolated cytoplasm which may be infiltrated by polymorpho-nuclear leucocytes is unremarkable. Some nuclei usually show transparent center surrounded by a rim of chromatin. The nucleoli are prominent. Marked vacuoles in the nucleus is observed. These findings are very important cytomorphologic characteristics for differential diagnosis between eosinophilic cystitis and malignant bladder tumor and cystitis due to bacterial infection.
描述了两名服用抗过敏药物（曲尼司特）引起嗜酸性膀胱炎患者的排尿标本的细胞形态学特征。尿路上皮细胞倾向于聚集成簇，大小不一。在细胞质中观察到明显的空泡化。显著空泡化的细胞质可能被多形核白细胞浸润，这并不罕见。一些细胞核通常显示透明的中心，周围有一圈染色质。核仁突出。在细胞核中观察到明显的空泡。这些发现是嗜酸性膀胱炎与恶性膀胱肿瘤及细菌感染所致膀胱炎进行鉴别诊断非常重要的细胞形态学特征。
