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非骨水泥复合髋臼假体周围骨改建:假体几何形状和假体-骨界面条件的影响。

Bone remodelling around cementless composite acetabular components: the effects of implant geometry and implant-bone interfacial conditions.

机构信息

Department of Mechanical Engineering, Indian Institute of Technology Kharagpur, Kharagpur 721 302, West Bengal, India.

Department of Mechanical Engineering, Indian Institute of Technology Kharagpur, Kharagpur 721 302, West Bengal, India.

出版信息

J Mech Behav Biomed Mater. 2014 Apr;32:257-269. doi: 10.1016/j.jmbbm.2014.01.010. Epub 2014 Jan 23.

Abstract

Recent developments in acetabular implants suggest flexible, alternative bearing material that may reduce wear and peri-prosthetic bone resorption. The goal of this study was to investigate the deviations in load transfer and the extent of bone remodelling around composite acetabular components having different geometries, material properties and implant-bone interface conditions, using 3-D FE analysis and bone remodelling algorithm. Variation in prosthesis type and implant-bone interface conditions affected peri-prosthetic strain distribution and bone remodelling. Strain shielding was considerably higher for bonded implant-bone interface condition as compared to debonded implant-bone interface condition. The average bone deformation (0.133mm) for horseshoe-shaped CFR-PEEK (resembling MITCH PCR(TM) cup) was very close to that of the intact acetabulum (0.135mm) at comparable locations. A reduction in bone density of 21-50% was predicted within the acetabulum for the implant resembling Cambridge cup, having bonded interface. For debonded interface condition, bone density increase of ~55% was observed in the supero-posterior part of acetabulum, whereas bone density reductions were low (1-20%) in other locations. Bone density reductions were considerably less (2-4%) for horseshoe-shaped CFR-PEEK component. Moreover, an increase in bone density of 1-87% was predicted around the acetabulum. Compared to the horseshoe-shaped design, the hemispherical design exacerbated bone resorption. Results indicated that the thickness of the acetabular component played a crucial role in the implant induced bone adaptation. The horseshoe-shaped CFR-PEEK component of 3mm thickness seemed a better alternative bearing surface than other designs, with regard to strain shielding, bone deformation and bone remodelling.

摘要

最近在髋臼植入物方面的发展表明,使用具有不同几何形状、材料特性和植入物-骨界面条件的复合髋臼部件,可采用 3D FE 分析和骨重塑算法来研究负载传递的偏差和周围骨重塑的程度。假体类型和植入物-骨界面条件的变化会影响假体周围的应变分布和骨重塑。与非结合植入物-骨界面条件相比,结合植入物-骨界面条件的应变屏蔽要高得多。马蹄形 CFR-PEEK(类似于 MITCH PCR(TM)杯)的平均骨变形(0.133mm)与可比位置的完整髋臼(0.135mm)非常接近。在具有结合界面的类似于剑桥杯的植入物中,预测髋臼内的骨密度降低 21-50%。对于具有非结合界面的条件,在髋臼的上后部分观察到约 55%的骨密度增加,而在其他位置的骨密度降低较低(1-20%)。马蹄形 CFR-PEEK 组件的骨密度降低幅度较小(2-4%)。此外,还预测髋臼周围的骨密度增加了 1-87%。与马蹄形设计相比,半球形设计加剧了骨吸收。结果表明,髋臼部件的厚度在植入物诱导的骨适应中起着至关重要的作用。与其他设计相比,3mm 厚的马蹄形 CFR-PEEK 组件在应变屏蔽、骨变形和骨重塑方面似乎是更好的替代轴承表面。

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