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全踝关节置换术后胫骨周围的骨重塑:植入物材料及植入物-骨界面条件的影响

Bone remodelling around the tibia due to total ankle replacement: effects of implant material and implant-bone interfacial conditions.

作者信息

Mondal Subrata, Ghosh Rajesh

机构信息

School of Engineering, Indian Institute of Technology Mandi , Mandi , India.

出版信息

Comput Methods Biomech Biomed Engin. 2019 Dec;22(16):1247-1257. doi: 10.1080/10255842.2019.1661385. Epub 2019 Sep 9.

DOI:10.1080/10255842.2019.1661385
PMID:31497997
Abstract

One of the major causes of implant loosening is due to excessive bone resorption surrounding the implant due to bone remodelling. The objective of the study is to investigate the effects of implant material and implant-bone interface conditions on bone remodelling around tibia bone due to total ankle replacement. Finite element models of intact and implanted ankles were developed using CT scan data sets. Bone remodelling algorithm was used in combination with FE analysis to predict the bone density changes around the ankle joint. Dorsiflexion, neutral, and plantar flexion positions were considered, along with muscle force and ligaments. Implant-bone interfacial conditions were assumed as debonded and bonded to represent non-osseointegration and fully osseointegration at the porous coated surface of the implant. To investigate the effect of implant material, three finite element models having different material combinations of the implant were developed. For model 1, tibial and talar components were made of Co-Cr-Mo, and meniscal bearing was made of UHMWPE. For model 2, tibial and talar components were made of ceramic and meniscal bearing was made of UHMWPE. For model 3, tibial and talar components were made of ceramic and meniscal bearing was made of CFR-PEEK. Changes in implant material showed no significant changes in bone density due to bone remodelling. Therefore, ceramic appears to be a viable alternative to metal and CFR-PEEK can be used in place of UHMWPE. This study also indicates that proper bonding between implant and bone is essential for long-term survival of the prosthetic components.

摘要

种植体松动的主要原因之一是由于骨重塑导致种植体周围过度的骨吸收。本研究的目的是调查种植体材料和种植体-骨界面条件对全踝关节置换术后胫骨周围骨重塑的影响。利用CT扫描数据集建立了完整和植入踝关节的有限元模型。骨重塑算法与有限元分析相结合,用于预测踝关节周围的骨密度变化。考虑了背屈、中立和跖屈位置,以及肌肉力量和韧带。种植体-骨界面条件假定为脱粘和粘结,以代表种植体多孔涂层表面的非骨整合和完全骨整合。为了研究种植体材料的影响,建立了三种具有不同种植体材料组合的有限元模型。模型1中,胫骨和距骨部件由钴铬钼制成,半月板承托由超高分子量聚乙烯制成。模型2中,胫骨和距骨部件由陶瓷制成,半月板承托由超高分子量聚乙烯制成。模型3中,胫骨和距骨部件由陶瓷制成,半月板承托由碳纤维增强聚醚醚酮制成。种植体材料的变化在骨重塑导致的骨密度方面没有显示出显著变化。因此,陶瓷似乎是金属的可行替代品,碳纤维增强聚醚醚酮可以用来代替超高分子量聚乙烯。本研究还表明,种植体与骨之间的适当结合对于假体部件的长期存活至关重要。

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