Vyskocil Erich, Gruther Wolfgang, Steiner Irene, Schuhfried Othmar
From the Department of Physical Medicine and Rehabilitation (EV, WG, OS) and Center for Medical Statistics, Informatics, and Intelligent Systems, Section for Medical Statistics (IS), Medical University Vienna, Vienna, Austria.
Am J Phys Med Rehabil. 2014 Jul;93(7):570-8. doi: 10.1097/PHM.0000000000000063.
Disease-specific categories of the International Classification of Functioning, Disability and Health have not yet been described for patients with chronic peripheral arterial obstructive disease (PAD). The authors examined the relationship between the categories of the Brief Core Sets for ischemic heart diseases with the Peripheral Artery Questionnaire and the ankle-brachial index to determine which International Classification of Functioning, Disability and Health categories are most relevant for patients with PAD.
This is a retrospective cohort study including 77 patients with verified PAD. Statistical analyses of the relationship between International Classification of Functioning, Disability and Health categories as independent variables and the endpoints Peripheral Artery Questionnaire or ankle-brachial index were carried out by simple and stepwise linear regression models adjusting for age, sex, and leg (left vs. right).
The stepwise linear regression model with the ankle-brachial index as dependent variable revealed a significant effect of the variables blood vessel functions and muscle endurance functions. Calculating a stepwise linear regression model with the Peripheral Artery Questionnaire as dependent variable, a significant effect of age, emotional functions, energy and drive functions, carrying out daily routine, as well as walking could be observed.
This study identifies International Classification of Functioning, Disability and Health categories in the Brief Core Sets for ischemic heart diseases that show a significant effect on the ankle-brachial index and the Peripheral Artery Questionnaire score in patients with PAD. These categories provide fundamental information on functioning of patients with PAD and patient-centered outcomes for rehabilitation interventions.
国际功能、残疾和健康分类（ICF）中针对慢性外周动脉阻塞性疾病（PAD）患者的疾病特定类别尚未被描述。作者研究了缺血性心脏病简要核心集的类别与外周动脉问卷及踝臂指数之间的关系，以确定ICF的哪些类别与PAD患者最为相关。
这是一项回顾性队列研究，纳入了77例确诊为PAD的患者。以ICF类别作为自变量，以外周动脉问卷或踝臂指数作为终点，通过简单和逐步线性回归模型进行统计分析，并对年龄、性别和腿（左或右）进行校正。
以踝臂指数为因变量的逐步线性回归模型显示血管功能和肌肉耐力功能变量具有显著影响。以外周动脉问卷为因变量计算逐步线性回归模型时，可观察到年龄、情绪功能、能量和动力功能、日常生活活动以及步行具有显著影响。
本研究确定了缺血性心脏病简要核心集中的ICF类别，这些类别对PAD患者的踝臂指数和外周动脉问卷得分有显著影响。这些类别提供了关于PAD患者功能以及康复干预以患者为中心的结局的基本信息。
