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本文引用的文献

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Virulence gene regulation by CvfA, a putative RNase: the CvfA-enolase complex in Streptococcus pyogenes links nutritional stress, growth-phase control, and virulence gene expression.CvfA(一种假定的 RNA 酶)对毒力基因的调节:酿脓链球菌中 CvfA-烯醇酶复合物将营养胁迫、生长阶段控制和毒力基因表达联系起来。
Infect Immun. 2010 Jun;78(6):2754-67. doi: 10.1128/IAI.01370-09. Epub 2010 Apr 12.
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Molecular mechanisms underlying group A streptococcal pathogenesis.A 组链球菌发病机制的分子机制。
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The global burden of group A streptococcal diseases.A组链球菌疾病的全球负担。
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Persistence of Streptococcus pyogenes in stationary-phase cultures.化脓性链球菌在稳定期培养物中的持续存在。
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Virulence factor regulation and regulatory networks in Streptococcus pyogenes and their impact on pathogen-host interactions.化脓性链球菌中的毒力因子调控及调控网络及其对病原体-宿主相互作用的影响。
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A secondary RNA polymerase sigma factor from Streptococcus pyogenes.一种来自化脓性链球菌的次要RNA聚合酶σ因子。
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7
Geographic and temporal distribution and molecular characterization of two highly pathogenic clones of Streptococcus pyogenes expressing allelic variants of pyrogenic exotoxin A (Scarlet fever toxin).表达致热外毒素A等位变体(猩红热毒素)的化脓性链球菌两个高致病性克隆的地理和时间分布及分子特征
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Growth characteristics of group A streptococci in a new chemically defined medium.A组链球菌在一种新的化学成分明确的培养基中的生长特性。
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化脓性链球菌(A 组链球菌,GAS)的实验室培养与保存

Laboratory growth and maintenance of Streptococcus pyogenes (the Group A Streptococcus, GAS).

作者信息

Gera Kanika, McIver Kevin S

机构信息

Department of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland.

出版信息

Curr Protoc Microbiol. 2013 Oct 2;30:9D.2.1-9D.2.13. doi: 10.1002/9780471729259.mc09d02s30.

DOI:10.1002/9780471729259.mc09d02s30
PMID:24510893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3920295/
Abstract

Streptococcus pyogenes is a Gram-positive bacterium that strictly infects humans. It is the causative agent of a broad spectrum of diseases accounting for millions of infections and at least 517,000 deaths each year worldwide. It is a nutritionally fastidious organism that ferments sugars to produce lactic acid and has strict requirements for growth. To aid in the study of this organism, this unit describes the growth and maintenance of S. pyogenes.

摘要

化脓性链球菌是一种严格感染人类的革兰氏阳性细菌。它是多种疾病的病原体,全球每年导致数百万例感染,至少51.7万人死亡。它是一种营养苛求型微生物,能发酵糖类产生乳酸,对生长有严格要求。为了辅助对这种微生物的研究,本单元描述了化脓性链球菌的培养和保存方法。