Department of Neurology, University of Washington Medical Center and Harborview Medical Center, Seattle, WA, USA.
Headache. 2014 Mar;54(3):583-90. doi: 10.1111/head.12304. Epub 2014 Feb 11.
Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population.
There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascular disease and connections between migraine and endothelial, structural, and genetic risk are reviewed.
There may be an interaction between endothelial dysfunction and cortical spreading depression affecting risk. Patient education and treatment of modifiable risk factors may decrease future vascular events.
偏头痛是一种常见的原发性头痛疾病，主要发生在年轻且相对健康的人群中。
目前有越来越多的文献探讨偏头痛（尤其是有先兆的偏头痛）与缺血性中风以及其他血管事件之间的关联。本文综述了偏头痛作为血管疾病的危险因素，以及偏头痛与血管内皮功能、结构和遗传风险之间的联系。
内皮功能障碍和皮质扩散性抑制之间可能存在相互作用，从而影响风险。对患者进行教育以及治疗可改变的危险因素可能会降低未来发生血管事件的风险。
