Department of Applied Chemistry, College of Science, China Agricultural University , Beijing 100193, People's Republic of China.
J Agric Food Chem. 2014 Apr 30;62(17):3710-25. doi: 10.1021/jf405240j. Epub 2014 Feb 20.
This study reports the development and validation of a novel rapid cleanup method based on multiple-walled carbon nanotubes in a packed column filtration procedure for analysis of pesticide residues followed by gas chromatography-triple-quadruple tandem mass spectrometry detection. The cleanup method was carried out by applying the streamlined procedure on a multiplug filtration cleanup column with syringes. The sorbent used for removing the interferences in the matrices is multiple-walled carbon nanotubes mixed with anhydrous magnesium sulfate. The proposed cleanup method is convenient and time-saving as it does not require any solvent evaporation, vortex, or centrifugation procedures. It was validated on 186 pesticides and 3 tomato product matrices spiked at two concentration levels of 10 and 100 μg kg(-1). Satisfactory recoveries and relative standard deviations are shown for most pesticides using the multiplug filtration cleanup method in tomato product samples. The developed method was successfully applied to the determination of pesticide residues in market samples.
本研究报告了一种基于多壁碳纳米管的新型快速净化方法的开发和验证，该方法采用填充柱过滤程序，随后进行气相色谱-三重四极串联质谱检测，用于分析农药残留。净化方法通过在多插件过滤净化柱上应用简化程序，用注射器进行。用于去除基质中干扰物的吸附剂是与无水硫酸镁混合的多壁碳纳米管。所提出的净化方法方便、省时，因为它不需要任何溶剂蒸发、涡旋或离心步骤。该方法在两个浓度水平（10 和 100μgkg(-1)）下对 186 种农药和 3 种番茄产品基质进行了验证。使用多插件过滤净化方法在番茄产品样品中，大多数农药的回收率和相对标准偏差都令人满意。所开发的方法成功应用于市场样品中农药残留的测定。
