School of Chemistry and Pharmaceutical Engineering, Shandong First Medical University, Shandong Academy of Medical Sciences, Tai'an 271016, China.
Key Laboratory of Pesticide Toxicology & Application Technique, College of Plant Protection, Shandong Agricultural University, Tai'an 271018, China.
Molecules. 2023 Mar 8;28(6):2480. doi: 10.3390/molecules28062480.
A survey was designed to investigate the pesticide residues in agricultural produce and to estimate their potential intake risks to inhabitants. A total of 314 samples of nine types of fruits and vegetables were collected from the supermarkets and vegetable markets of Shandong Province (China) from October 2020 to February 2022. An accurate and reliable multi-residue method, based on GC-MS/MS detection, as well as the multiplug filtration cleanup method, based on SBA-15-C, was prepared by a solution chemical reaction. Additionally, an in situ co-condensation method was established for the quantification of 139 pesticide residues. Residues that contained no pesticides were detected in 66.5% of the 314 samples. Moreover, of the samples, 30.6% were at or below the MRLs, and 2.9% were above the MRLs. Residues of procymidone were found to be the one that most often exceeded the MRLs (1.3% of the samples). Tebuconazole was found most frequently in 22.0% of the samples analyzed. Consumer exposure to the 139 pesticides did not exceed 100% ADI and ARfD. This led to a consideration that these pesticide residues in the nine commodities may not raise the health risk of the consumers in the long and short term. The highest value of chronic dietary intake was obtained from spirodiclofen, which resulted in a 24.1% of ADI. Furthermore, the highest exposure levels in the short term were obtained from the consumption of leeks with procymidone (58.3% ARfD).
这项调查旨在研究农产品中的农药残留，并评估其对居民潜在的摄入量风险。2020 年 10 月至 2022 年 2 月，从山东省的超市和菜市场采集了 314 个水果和蔬菜样本，共 9 种。基于 GC-MS/MS 检测的准确可靠的多残留方法和基于 SBA-15-C 的多插件过滤净化方法（基于 SBA-15-C），通过溶液化学反应进行了制备。此外，建立了一种原位共缩聚方法，用于定量分析 139 种农药残留。在 314 个样本中，有 66.5%的样本未检出农药残留。此外，其中 30.6%的样本残留浓度低于或等于最大残留限量（MRL），2.9%的样本残留浓度高于 MRL。检测到残留量最高的是噻菌灵（procymidone），有 1.3%的样本超过了 MRL。三唑醇（tebuconazole）在分析的 22.0%的样本中最常被检出。消费者对 139 种农药的暴露量未超过 100%ADI 和 ARfD。这表明在长期和短期内，这些九种商品中的农药残留可能不会对消费者的健康构成风险。从慢性膳食摄入的最高值来自螺虫乙酯（spirodiclofen），占 ADI 的 24.1%。此外，短期摄入的最高暴露水平来自食用含有噻菌灵的韭菜（58.3% ARfD）。
