内脏利什曼病患者尿液中杜氏利什曼原虫可溶性抗原及抗体的检测
Detection of Leishmania donovani soluble antigen and antibody in the urine of visceral leishmaniasis patients.
作者信息
Kohanteb J, Ardehali S M, Rezai H R
机构信息
Department of Microbiology, Medical School, Shiraz University, Iran.
出版信息
Trans R Soc Trop Med Hyg. 1987;81(4):578-80. doi: 10.1016/0035-9203(87)90414-7.
PMID:2451331
Abstract
Urine samples from 21 patients with visceral leishmaniasis were examined for the presence of Leishmania donovani soluble antigen and antibody by double counter-current immunoelectrophoresis. 19 samples revealed both antigen and antibody (IgM in 5 and IgG in all samples). 2 urine samples collected 10 and 13 days after Glucantime treatment revealed only antibody (IgG), not soluble antigen.
摘要
采用双向对流免疫电泳法检测了21例内脏利什曼病患者尿液样本中的杜氏利什曼原虫可溶性抗原和抗体。19份样本同时检测到抗原和抗体（5份样本中有IgM，所有样本中均有IgG）。在使用葡糖胺锑治疗10天和13天后采集的2份尿液样本中仅检测到抗体（IgG），未检测到可溶性抗原。
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