Höckenström T, Jonassen F, Knutsson F, Löwhagen G B, Rådberg T
Department of Pathology, University of Gothenburg, Sahlgren's Hospital, Sweden.
Acta Derm Venereol. 1987;67(6):511-6.
Altogether 51 regular female consorts of men attending a venereal disease clinic for genital warts were examined using colposcopy, vaginal cytology and--when needed--surgical biopsy. Abnormal cytological smears were found in 18 out of 49 consorts (37%), which should be compared with 8 out of 124 (6%) matched female controls from a family planning clinic (p less than 0.001). Possibly premalignant lesions, i.e. atypical condylomata and/or frank dysplasia, were found in 14 (27%) out of 51 consorts. The prevalence of abnormal smears or biopsy-proven dysplasia was approximately the same in consorts with and without external warts. These findings call for close attention to the risk of development of cervical dysplasia in female consorts of men with genital warts.
共有51名男性尖锐湿疣患者的正常女性性伴接受了阴道镜检查、阴道细胞学检查，必要时还进行了手术活检。49名性伴中有18名（37%）细胞学涂片异常，与之相比，来自计划生育门诊的124名配对女性对照中有8名（6%）异常（p<0.001）。51名性伴中有14名（27%）发现了可能为癌前病变，即非典型湿疣和/或明显发育异常。有或无外生殖器湿疣的性伴中，涂片异常或活检证实的发育异常患病率大致相同。这些发现提示，对于患有尖锐湿疣男性的女性性伴，应密切关注其发生宫颈发育异常的风险。
