J Neuropsychiatry Clin Neurosci. 2014 Winter;26(1):5-23. doi: 10.1176/appi.neuropsych.12120403.
The authors critically reviewed all relevant peer-reviewed quantitative research pertaining to the risk factors for psychosis secondary to temporal lobe epilepsy, carrying out an extensive literature search to identify all relevant research studies, and applying specific exclusion criteria; the search yielded 27 original research articles for critical review. These studies were individually assessed for methodological quality. Authors reached consensus on a number of important risk factors for psychosis, including early age at epilepsy onset, history of status epilepticus, hippocampal sclerosis, and left-hemisphere abnormalities. Inconsistencies in defining and diagnosing epileptic psychoses were apparent, as well as the sole use of case-control, cross-sectional, and/or retrospective study designs. There remains a need for research using consistent classification criteria and longitudinal study designs.
作者对所有与颞叶癫痫继发精神病的危险因素相关的、经过同行评审的定量研究进行了批判性回顾，开展了广泛的文献检索以确定所有相关的研究，并应用了特定的排除标准；该检索共产生了 27 篇原始研究文章供批判性评价。对这些研究进行了个体的方法学质量评估。作者就若干重要的精神病风险因素达成共识，包括癫痫发病年龄早、癫痫持续状态史、海马硬化和左侧半球异常。在癫痫性精神病的定义和诊断方面存在不一致，并且仅使用病例对照、横断面和/或回顾性研究设计。因此，仍然需要使用一致的分类标准和纵向研究设计开展研究。
