Anyfantakis Dimitrios, Symvoulakis Emmanouil K, Barbounakis Emmanouil, Kastanakis Miltiades, Athanasakis Evangelos, Blevrakis Evangelos, Kastanakis Serafeim
Primary Health Care Centre of Kissamos , Kissamos, Crete , Greece.
Mod Rheumatol. 2014 Sep;24(5):858-61. doi: 10.3109/14397595.2013.874743. Epub 2014 Feb 11.
Systemic lupus erythematosus is a multisystemic, autoimmune, inflammatory disorder predominantly affecting young females. Its onset may be abrupt or insidious, presenting with a broad range of clinical and immunological features. We report an unusual case of elderly-onset systemic lupus erythematosus in a woman initially diagnosed with discoid lupus, and subsequently admitted to hospital due to a progressive psycho-motor deficit. Electrophysiological measurements suggested a diagnosis of acute motor sensory axonal neuropathy. Unusual clinical features and negative serology led to diagnostic uncertainty. This case report offers information on the course of the disease through the entire chain of the health care delivery (from primary to tertiary). Despite the efforts of the hospital staff, it was not possible to save the life of the woman.
系统性红斑狼疮是一种多系统的自身免疫性炎症性疾病，主要影响年轻女性。其起病可能突然或隐匿，表现出广泛的临床和免疫学特征。我们报告一例老年系统性红斑狼疮的罕见病例，该女性最初被诊断为盘状狼疮，随后因进行性精神运动功能障碍入院。电生理测量提示急性运动感觉轴索性神经病的诊断。不寻常的临床特征和血清学阴性导致诊断存在不确定性。本病例报告提供了该疾病在整个医疗服务链（从初级到三级）中的病程信息。尽管医院工作人员做出了努力，但仍未能挽救该女性的生命。
