Aggarwal H K, Jain D, Mittal A, Rao A, Yadav R K, Jain P
Department of Medicine, Pt. B.D. Sharma University of Health Sciences, Rohtak.
Reumatismo. 2016 Jun 23;68(1):48-52. doi: 10.4081/reumatismo.2016.846.
We report a case of 19 year-old female patient diagnosed as systemic lupus erythematosus (SLE) presented with fever and diffuse cutaneous lesions. During the hospital stay she had acute pneumonia, pleural effusion and respiratory failure, which required intensive care unit (ICU) care and mechanical ventilator support. A fulminant course of the disease, decreased values of complement levels and positive antinuclear antibodies (ANA) in pleural fluid and repeated negative sputum for acid-fast bacillus, blood cultures enabled diagnosis of fulminant lupus pneumonitis. Fulminant lupus pneumonitis is a rare but potentially life threatening complication of SLE. Management requires involvement of multiple specialties and rigorous efforts in reviving the patient.
我们报告了一例19岁女性患者，被诊断为系统性红斑狼疮（SLE），出现发热和弥漫性皮肤病变。住院期间，她发生了急性肺炎、胸腔积液和呼吸衰竭，需要重症监护病房（ICU）护理和机械通气支持。病情呈暴发性经过，胸腔积液中补体水平降低、抗核抗体（ANA）阳性，多次痰涂片抗酸杆菌阴性、血培养阴性，从而诊断为暴发性狼疮肺炎。暴发性狼疮肺炎是SLE一种罕见但可能危及生命的并发症。治疗需要多个专科参与，并为挽救患者付出巨大努力。
