Praetorius Christian, Sturm Richard A, Steingrimsson Eirikur
Department of Biochemistry and Molecular Biology, Biomedical Center, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Pigment Cell Melanoma Res. 2014 May;27(3):339-50. doi: 10.1111/pcmr.12232. Epub 2014 Mar 3.
Freckles, the lay term for ephelides and lentigines, are important pigmentation characteristics observed in humans. Both are affected by sunlight; ephelides are largely genetically determined but induced by sunlight, whereas lentigines are induced by sun exposure and photodamage of the skin. However, despite being commonly observed, we know very little about them. Here, we review the current status of knowledge about freckles and propose a model for their formation.
雀斑是雀斑样痣和色素沉着斑的通俗说法，是人类观察到的重要色素沉着特征。两者都受阳光影响；雀斑样痣很大程度上由基因决定，但由阳光诱发，而色素沉着斑是由阳光照射和皮肤光损伤诱发的。然而，尽管它们很常见，但我们对它们的了解却很少。在这里，我们综述了关于雀斑的现有知识状况，并提出了一个雀斑形成的模型。
