Shurrab Kawthar, Alzghayar Juliana Nabil
Higher Institute for Laser Research and Applications, Damascus University, Damascus, Syria.
Case Rep Dermatol Med. 2025 Aug 10;2025:8197442. doi: 10.1155/crdm/8197442. eCollection 2025.
Facial pigmentation disorders such as ephelides (commonly known as freckles) and solar lentigines are chronic dermatological conditions associated with sun exposure that can impact cosmetic appearance. This case report presents low-level laser therapy (LLLT) as an effective intervention for two different pigmentary disorders in Syrian women: one with ephelides and another with solar lentigines. The first case involved a 34-year-old woman with Fitzpatrick skin type II presenting with facial ephelides, while the second case featured a 49-year-old woman with Fitzpatrick skin type III diagnosed with solar lentigo. Both patients underwent 12 sessions from June 1 to August 1, 2023, using a red diode laser (660 nm) at a power density of 15.6 mW/cm and a dose of 5.6 J/cm, applied for 6 min per session, with one pass per treatment area. The results demonstrated a marked reduction in pigmentation intensity and lesion size, with no reported side effects or lesion recurrence during a 1-year follow-up. These results suggest that LLLT may serve as an effective and safe therapeutic modality for selected facial pigmentary disorders.
面部色素沉着紊乱，如雀斑（俗称晒斑）和日光性黑子，是与日晒相关的慢性皮肤病，会影响外貌。本病例报告介绍了低强度激光疗法（LLLT）作为对两名叙利亚女性不同色素沉着紊乱的有效干预措施：一名患有雀斑，另一名患有日光性黑子。第一例是一名34岁、皮肤为菲茨帕特里克II型的女性，患有面部雀斑；第二例是一名49岁、皮肤为菲茨帕特里克III型的女性，被诊断为日光性黑子。两名患者于2023年6月1日至8月1日接受了12次治疗，使用红色二极管激光（660纳米），功率密度为15.6毫瓦/平方厘米，剂量为5.6焦/平方厘米，每次治疗区域照射6分钟，每次照射一遍。结果显示色素沉着强度和皮损大小显著降低，在1年的随访中未报告有副作用或皮损复发。这些结果表明，LLLT可能是治疗某些面部色素沉着紊乱的一种有效且安全的治疗方式。
