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脆性骨折后教育干预对骨质疏松症可改变危险因素的影响。

The impact of educational interventions on modifiable risk factors for osteoporosis after a fragility fracture.

作者信息

Beaudoin C, Bessette L, Jean S, Ste-Marie L-G, Brown J P

机构信息

CHU de Québec Research Centre, 2705, Boulevard Laurier, S-769C, Québec, G1V 4G2, Canada,

出版信息

Osteoporos Int. 2014 Jul;25(7):1821-30. doi: 10.1007/s00198-014-2618-4. Epub 2014 Feb 12.

Abstract

The purpose of this study was to investigate the impact of two educational interventions on the intake of calcium and vitamin D supplements and modifiable risk factors for osteoporosis in women ≥50 years with a fragility fracture (FF). Within 6-8 months of fracture, women were randomized to one of three intervention groups: usual care (UC), written materials (WM), or videocassette and written materials (VC). The written materials for patients and their physician provided information on osteoporosis, FF, and available treatments; written materials for physician were provided through patients. The videocassette presented similar information as the written material, but in greater depth. Twelve months after randomization, the effectiveness of the interventions was assessed. The study cohort consisted of 1,175 women undiagnosed and untreated for osteoporosis. After 12 months, the mean intake of Ca supplements increased by 33, 93, and 91 mg/day for the UC, WM, and VC groups, respectively (p value, WM vs UC = 0.163; VC vs UC = 0.026); the corresponding mean increases for vitamin D were 58, 105, and 118 IU/day (p value, WM vs UC = 0.214; VC vs UC = 0.012). The proportion of women who increased their Ca and vitamin D intake by supplements was similar in all three groups. The intervention had a greater impact in those not taking supplements at randomization and had no impact on modifiable risk factors. In women without diagnosis and treatment for osteoporosis, the interventions seem effective at increasing the amounts of Ca and vitamin D supplements, but not effective at inciting more women to increase their consumption. Therefore, the clinical significance of the impact of the intervention is difficult to evaluate.

摘要

本研究旨在调查两种教育干预措施对50岁及以上患有脆性骨折(FF)的女性补充钙和维生素D的摄入量以及骨质疏松症可改变风险因素的影响。在骨折后的6至8个月内,将女性随机分为三个干预组之一:常规护理(UC)、书面材料(WM)或录像带加书面材料(VC)。为患者及其医生提供的书面材料包含有关骨质疏松症、脆性骨折和可用治疗方法的信息;为医生提供的书面材料通过患者传递。录像带呈现了与书面材料类似的信息,但更深入。随机分组12个月后,评估干预措施的有效性。研究队列由1175名未被诊断和未接受骨质疏松症治疗的女性组成。12个月后,UC组、WM组和VC组钙补充剂的平均摄入量分别增加了33、93和91毫克/天(p值,WM组与UC组比较=0.163;VC组与UC组比较=0.026);维生素D的相应平均增加量分别为58、105和118国际单位/天(p值,WM组与UC组比较=0.214;VC组与UC组比较=0.012)。三组中通过补充剂增加钙和维生素D摄入量的女性比例相似。该干预措施对随机分组时未服用补充剂的女性影响更大,对可改变的风险因素没有影响。在未诊断和未治疗骨质疏松症的女性中,这些干预措施似乎在增加钙和维生素D补充剂的摄入量方面有效,但在促使更多女性增加摄入量方面无效。因此,干预措施影响的临床意义难以评估。

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