Institute for Organic Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131 Karlsruhe (Germany) http://www.paradies-group.de.
Angew Chem Int Ed Engl. 2014 Apr 1;53(14):3552-7. doi: 10.1002/anie.201309253. Epub 2014 Feb 12.
The metal-free activation of hydrogen by frustrated Lewis pairs (FLPs) is a valuable method for the hydrogenation of polarized unsaturated molecules ranging from imines, enamines, and silyl enol ethers to heterocycles. However, one of the most important applications of hydrogenation technology is the conversion of unsaturated hydrocarbons into alkanes or alkenes. Despite the fast development of the FLP chemistry, such reactions proved as highly challenging. This Minireview provides an overview of the basic concepts of FLP chemistry, the challenge in the hydrogenation of unsaturated hydrocarbons, and first solutions to this central transformation.
无金属氢活化的路易斯酸对（FLPs）是一种很有价值的方法，可用于对从亚胺、烯胺和硅基烯醇醚到杂环的各种极化不饱和分子进行氢化。然而，氢化技术最重要的应用之一是将不饱和烃转化为烷烃或烯烃。尽管 FLP 化学发展迅速，但这类反应极具挑战性。这篇综述介绍了 FLP 化学的基本概念、不饱和烃氢化的挑战，以及该中心转化的初步解决方案。
