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2
Longan (Dimocarpus longan Lour.) inhibits lipopolysaccharide-stimulated nitric oxide production in macrophages by suppressing NF-κB and AP-1 signaling pathways.龙眼(Dimocarpus longan Lour.)通过抑制核因子κB(NF-κB)和活化蛋白-1(AP-1)信号通路,抑制巨噬细胞中脂多糖刺激的一氧化氮生成。
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Longan Flower Ethanol Extract, Lour, Mitigates Oxidative Damage and Inflammatory Responses While Promoting Sleep-Related Enzymes in Cell Models.龙眼花乙醇提取物(Lour.)在细胞模型中减轻氧化损伤和炎症反应,同时促进与睡眠相关的酶。
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Litchi seed extract inhibits epidermal growth factor receptor signaling and growth of Two Non-small cell lung carcinoma cells.荔枝核提取物抑制表皮生长因子受体信号传导及两种非小细胞肺癌细胞的生长。
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Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials.常规阿司匹林对长期癌症发病率和转移的影响:来自观察性研究与随机试验证据的系统比较。
Lancet Oncol. 2012 May;13(5):518-27. doi: 10.1016/S1470-2045(12)70112-2. Epub 2012 Mar 21.
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Cancer chemoprevention by carotenoids.类胡萝卜素的癌症化学预防。
Molecules. 2012 Mar 14;17(3):3202-42. doi: 10.3390/molecules17033202.
3
Mitochondria and cancer: a growing role in apoptosis, cancer cell metabolism and dedifferentiation.线粒体与癌症:在细胞凋亡、癌细胞代谢和去分化中作用不断增大。
Adv Exp Med Biol. 2012;942:287-308. doi: 10.1007/978-94-007-2869-1_13.
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Cancer stem cells and tumor angiogenesis.癌症干细胞与肿瘤血管生成。
Cancer Lett. 2012 Aug 1;321(1):13-7. doi: 10.1016/j.canlet.2012.02.024. Epub 2012 Feb 28.
5
The dietary phytochemical 3,3'-diindolylmethane induces G2/M arrest and apoptosis in oral squamous cell carcinoma by modulating Akt-NF-κB, MAPK, and p53 signaling.膳食植物化学物 3,3'-二吲哚甲烷通过调节 Akt-NF-κB、MAPK 和 p53 信号通路诱导口腔鳞状细胞癌的 G2/M 期阻滞和细胞凋亡。
Chem Biol Interact. 2012 Feb 5;195(3):224-30. doi: 10.1016/j.cbi.2012.01.003. Epub 2012 Jan 24.
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Health benefits of nut consumption.坚果的健康益处。
Nutrients. 2010 Jul;2(7):652-682. doi: 10.3390/nu2070652. Epub 2010 Jun 24.
7
Multiple degradation pathways regulate versatile CIP/KIP CDK inhibitors.多种降解途径调节多功能 CIP/KIP CDK 抑制剂。
Trends Cell Biol. 2012 Jan;22(1):33-41. doi: 10.1016/j.tcb.2011.10.004. Epub 2011 Dec 9.
8
Eicosanoid signalling pathways in the development and progression of colorectal cancer: novel approaches for prevention/intervention.类二十烷酸信号通路在结直肠癌发生和发展中的作用:预防/干预的新方法。
Cancer Metastasis Rev. 2011 Dec;30(3-4):363-85. doi: 10.1007/s10555-011-9324-x.
9
Pharmacology and cellular/molecular mechanisms of action of aspirin and non-aspirin NSAIDs in colorectal cancer.阿司匹林和非阿司匹林类 NSAIDs 在结直肠癌中的药理学和细胞/分子作用机制。
Best Pract Res Clin Gastroenterol. 2011 Aug;25(4-5):473-84. doi: 10.1016/j.bpg.2011.10.016.
10
Resveratrol interferes with N-nitrosodiethylamine-induced hepatocellular carcinoma at early and advanced stages in male Wistar rats.白藜芦醇在雄性 Wistar 大鼠早期和晚期阶段干扰 N-亚硝基二乙胺诱导的肝癌。
Mol Med Rep. 2011 Nov-Dec;4(6):1211-7. doi: 10.3892/mmr.2011.555. Epub 2011 Aug 16.

龙眼花和种子提取物在抗癌方面的潜在作用。

Potential roles of longan flower and seed extracts for anti-cancer.

作者信息

Lin Chih-Cheng, Chung Yuan-Chiang, Hsu Chih-Ping

机构信息

Chih-Cheng Lin, Department of Biotechnology, Yuanpei University, Hsinchu City 30015, Taiwan, China.

出版信息

World J Exp Med. 2012 Aug 20;2(4):78-85. doi: 10.5493/wjem.v2.i4.78.

DOI:10.5493/wjem.v2.i4.78
PMID:24520538
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3905590/
Abstract

Polyphenol-rich plants are known to possess benefits to human health. Recent studies have revealed that many Traditional Chinese Medicines (TCMs) are rich sources of polyphenols and exhibit antioxidant and anti-inflammatory activities, and these TCMs have been shown experimentally to overcome some chronic diseases, including cancer. Longan flowers and seeds, two TCMs traditionally used for relieving pain and urinary diseases, have been revealed in our recent reports and other studies to possess rich amounts of polyphenolic species and exhibit strong anti-oxidant activity, and these could be applied for the treatment of diabetes and cancer. Herein, we review the recent findings regarding the benefits of these two TCMs in the treatment of human cancer and the possible cellular and molecular mechanisms of both substances.

摘要

富含多酚的植物已知对人体健康有益。最近的研究表明,许多传统中药(TCM)是多酚的丰富来源,并具有抗氧化和抗炎活性,并且这些中药已通过实验证明可克服一些慢性疾病,包括癌症。龙眼花和种子是两种传统上用于缓解疼痛和泌尿系统疾病的中药,我们最近的报告和其他研究表明它们含有大量的多酚类物质并具有很强的抗氧化活性,这些可用于治疗糖尿病和癌症。在此,我们综述了关于这两种中药在治疗人类癌症方面的益处以及这两种物质可能的细胞和分子机制的最新研究结果。