Chen Lei, Zhu Ling, Zhou Yuan-Cheng, Guo Wan-Zhu
College of Veterinary Medicine of Sichuan Agricultural University, Ya'an 625014, China.
Bing Du Xue Bao. 2013 Nov;29(6):667-72.
Porcine Torovirus (PToV) is widely distributed in the world with high prevalence rate in swinery. Due to the high detection rate in diarrhea pigs, PToV is thought to be a potential pathogen of swine diarrhea. In recent years, epidemic outbreaks of diarrhea with high morbidity and mortality in China have caused great economic losses. Intertypic recombination events and antigenic cross-reactivity among toroviruses implies potential zoonotic transmission of PToV. The review represented the development history of PToV and made a brief summary of the features in genome and protein epidemiology and laboratory diagnosis of the PToV, and so on.
猪环曲病毒（PToV）在世界范围内广泛分布，在猪群中的感染率很高。由于在腹泻猪中的检出率较高，PToV被认为是猪腹泻的潜在病原体。近年来，中国腹泻病的流行暴发导致了高发病率和高死亡率，造成了巨大的经济损失。环曲病毒之间的型间重组事件和抗原交叉反应意味着PToV可能存在人畜共患病传播。本文综述了PToV的发展历程，并对其基因组特征、蛋白质流行病学及实验室诊断等方面进行了简要总结。
