Chen Zhi, Lin Sheng-Yun, Zhou Yu-Hong, Wu Li-Qiang, Zhang Ying, Shen Yi-Ping, Zheng Zhi-Yin, Chen Jun-Fa, Shen Ying-Ying, Chen Ying-Ying
Department of Hematology, First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou 310006, China.
Center for Clinical Assessment and Analysis, First Clinical College of Zhejiang Chinese Medical University, Hangzhou 310006, China.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Jan;34(1):43-5.
To study Chinese medicine (CM) syndrome types of chronic aplastic anemia (CAA) patients and the distribution laws of typical CM symptoms in different genders.
From June 2002 to June 2012, 220 CAA outpatients/inpatients at Department of Hematology, Zhejiang Chinese Medical Hospital were recruited. Patients' symptoms and signs, as well as four diagnostic information at the first onset were collected. CM syndrome differentiation was performed. The syndrome types and typical symptoms were analyzed.
(1) In the 220 CAA patients, there were 121 cases of Shen yang deficiency syndrome (55.0%), 18 of Shen yin deficiency syndrome type (8.18%), 81 cases of Shen yin-yang deficiency syndrome (36.82%). (2) The distribution of typical symptoms: fatigue and shortness of breath (77.12% males and 73.53% females), pale complexion (64.41% males and 57.84% females), low temperature of four limbs (12.71% males and 26.47% females), spontaneous perspiration and night sweating (32.20% males and 26.47% females), dry mouth and throat (6.78% males and 6.86% females), feverish feelings in palms and soles (14.41% males and 20.59% females), loose stool (6.78% males and 2.94% females), petechiae and ecchymosis (42.37% males and 43.14% females).
Shen yang deficiency syndrome was most often seen in CAA patients at the initial diagnosis, followed by Shen yin-yang deficiency syndrome. Shen yin deficiency syndrome was the least seen. In CM symptoms, fatigue and shortness of breath were most common seen, followed by pale complexion, skin petechia and ecchymosis.