Deeg H J, Ladiges W C, Aprile J, Schuening F, Raff R F, Storb R
Fred Hutchinson Cancer Research Center, Seattle, WA.
Methods Find Exp Clin Pharmacol. 1987 Nov;9(11):749-53.
A limited panel of mAbs directed at canine cell populations is available. The number of antibodies is growing, permitting us to learn more about functional properties of the respective cell populations both in vitro and in vivo. Studies such as those dealing with facilitation of engraftment or positive selection of stem cells will be of great importance in clinical marrow transplantation. Consequently, further studies in this canine model are desirable.
目前有一组针对犬类细胞群体的单克隆抗体。抗体的数量正在增加,这使我们能够更多地了解各个细胞群体在体外和体内的功能特性。诸如那些涉及促进移植或干细胞阳性选择的研究,在临床骨髓移植中将具有重要意义。因此,在这个犬类模型中进行进一步研究是很有必要的。