一系列识别日本猕猴（食蟹猴）白细胞分化抗原的单克隆抗体的研制。
Development of a series of monoclonal antibodies recognizing leukocyte differentiation antigens of Japanese monkeys (Macaca fuscata).
作者信息
Murayama Y, Noguchi A, Takenaka O
机构信息
Primate Research Institute, Kyoto University, Aichi, Japan.
出版信息
J Med Primatol. 1989;18(2):99-109.
PMID:2785602
Abstract
Six monoclonal antibodies to Japanese monkey leukocytes were developed. These monoclonal antibodies, designated the U series, cover most kinds of leukocytes (pan T cells, CD8+ cells, CD8+ subset and granulocytes, CD16+ cells, monocytes/macrophages), and should be useful in the immunological analysis of primate models, such as tissue transplants and virus-related diseases, in particular, acquired immune deficiency syndrome (AIDS).
摘要
开发出了六种针对日本猕猴白细胞的单克隆抗体。这些单克隆抗体被命名为U系列，覆盖了大多数种类的白细胞（全T细胞、CD8 +细胞、CD8 +亚群和粒细胞、CD16 +细胞、单核细胞/巨噬细胞），在灵长类动物模型的免疫分析中应该会很有用，比如组织移植和病毒相关疾病，特别是获得性免疫缺陷综合征（艾滋病）。
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