Shaw Souradet Y, Jolly Ann M, Wylie John L
Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Public Health Agency of Canada, Ottawa, Ontario, Canada ; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
PLoS One. 2014 Feb 11;9(2):e88623. doi: 10.1371/journal.pone.0088623. eCollection 2014.
We previously identified a high prevalence of Hepatitis C (HCV) amongst solvent-using injection drug users (S-IDU) relative to other injection drug users within the same locality. Here we incorporated social network variables to better characterize some of the behavioural characteristics that may be putting this specific subgroup of IDU at elevated disease risk.
A cross-sectional survey of at-risk populations was carried out in Winnipeg, Canada in 2009. Individuals reporting any history of injection drug and/or solvent use were included in the study. Associations between subgroup membership, infection with HCV and HIV and individual and social network variables were examined.
In relation to other IDU, S-IDU were more likely to be infected with HCV, to report ever having shared a syringe, and to associate with other IDU. They were further differentiated in terms of their self-reported sexual orientation, ethnicity and in the injection drugs typically used.
Solvent use stands as a proxy measure of numerous other characteristics that put this group of IDU at higher risk of infection. Provision of adequate services to ostracized subpopulations may result in wider population-level benefits.
我们之前发现,与同一地区的其他注射吸毒者相比,使用溶剂的注射吸毒者(S-IDU)中丙型肝炎(HCV)的患病率较高。在此,我们纳入了社交网络变量,以更好地描述可能使这一特定亚组注射吸毒者疾病风险升高的一些行为特征。
2009年在加拿大温尼伯对高危人群进行了横断面调查。报告有任何注射吸毒和/或使用溶剂史的个体被纳入研究。研究了亚组成员身份、HCV和HIV感染与个体及社交网络变量之间的关联。
与其他注射吸毒者相比,S-IDU感染HCV的可能性更高,报告曾共用过注射器,且与其他注射吸毒者有交往。他们在自我报告的性取向、种族以及通常使用的注射毒品方面也存在差异。
使用溶剂是众多其他使该组注射吸毒者感染风险更高的特征的替代指标。为受排斥的亚人群提供充分的服务可能会带来更广泛的人群层面的益处。