Haratake J, Horie A, Ishii N, Matsuo N, Lee S D
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Japan.
Acta Pathol Jpn. 1988 Jan;38(1):83-8. doi: 10.1111/j.1440-1827.1988.tb01074.x.
An unusual nodular transformation of the liver was found in a 53-year-old man with meningoencephalitis who died of brain stem herniation. Postmortem examination revealed marked neuronal ischemic changes and bronchopneumonia as well as meningoencephalitis. The liver showed no significant lesions macroscopically. Histologically, there were many small nodules, less than 1 mm in diameter and composed of clear hepatocytes, throughout the liver. The liver cells in these nodules showed mild hyperplastic changes. Many fine granules, stained by orcein and Victoria blue, were found exclusively in the hepatocytes of these nodules. We describe the peculiar histopathology of this case with reference to some related lesions.
在一名53岁患有脑膜脑炎并死于脑干疝的男性患者中发现了肝脏的一种不寻常的结节性转变。尸检显示有明显的神经元缺血性改变、支气管肺炎以及脑膜脑炎。肝脏大体上无明显病变。组织学检查发现，整个肝脏有许多直径小于1毫米、由透明肝细胞组成的小结节。这些结节中的肝细胞有轻度增生性改变。仅在这些结节的肝细胞中发现了许多被地衣红和维多利亚蓝染色的细颗粒。我们参考一些相关病变描述了该病例独特的组织病理学表现。
