Shousha S, Bull T B
Department of Histopathology, Charing Cross Hospital, London, UK.
Histopathology. 1988 Oct;13(4):455-8. doi: 10.1111/j.1365-2559.1988.tb02061.x.
A liver cell carcinoma removed surgically by partial hepatectomy from a 79-year-old woman contained abundant orcein-positive granules in many tumour cells. The granules were similar to those usually identified as representing copper-associated protein, yet they lacked copper, as demonstrated by negative rhodanine and rubeanic acid stains and energy dispersive X-ray microanalysis.