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肌萎缩侧索硬化后综合征的病理生理学和诊断。

Pathophysiology and diagnosis of post-polio syndrome.

机构信息

Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.

出版信息

NeuroRehabilitation. 1997;8(2):83-92. doi: 10.3233/NRE-1997-8203.

DOI:10.3233/NRE-1997-8203
PMID:24525979
Abstract

Post-poliomyelitis syndrome is defined as a clinical syndrome of new weakness, fatigue and pain which can occur several decades following recovery from paralytic poliomyelitis. The cause of this disorder is still unclear, and many possible etiologies have been proposed. The most widely accepted etiology was first proposed by Wiechers and Hubbell, which attributes PPS to a distal degeneration of massively enlarged post-polio motor units. Other probable contributing factors to the onset of this disease are the ageing process, and overuse. Currently, there is no specific diagnostic test for PPS, which continues to be a diagnosis of exclusion in an individual with symptoms and signs of the disorder.

摘要

后灰质炎综合征定义为一种新的虚弱、疲劳和疼痛的临床综合征,可在麻痹性脊髓灰质炎恢复后几十年发生。这种疾病的原因尚不清楚,提出了许多可能的病因。最广泛接受的病因学最初是由Wiechers 和 Hubbell 提出的,他们将 PPS 归因于大量增大的后灰质炎运动单位的远端变性。这种疾病发病的其他可能的促成因素是衰老过程和过度使用。目前,PPS 没有特定的诊断测试,在有症状和体征的个体中仍然是一种排除性诊断。

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Pathophysiology and diagnosis of post-polio syndrome.肌萎缩侧索硬化后综合征的病理生理学和诊断。
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2
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Predictive factors for post-poliomyelitis syndrome.小儿麻痹后遗症的预测因素。
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Post polio syndrome: an update for the primary health care provider.小儿麻痹后遗症:给初级卫生保健提供者的最新资讯
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Post-polio syndrome: historical perspective, epidemiology and clinical presentation.肌萎缩侧索硬化后综合征:历史视角、流行病学和临床表现。
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Post-polio hospital admissions in Australia over a 10-year period: An observational study and analysis of trends by month, location, and comparable conditions.澳大利亚10年间小儿麻痹症后住院情况:一项按月份、地点和可比病症进行趋势观察的研究与分析
J Public Health (Oxf). 2025 Aug 29;47(3):e262-e273. doi: 10.1093/pubmed/fdaf029.
2
Pain in persons with postpolio syndrome: frequency, intensity, and impact.小儿麻痹后遗症患者的疼痛:频率、强度及影响
Arch Phys Med Rehabil. 2008 Oct;89(10):1933-40. doi: 10.1016/j.apmr.2008.03.018.