Soltyszewski Ireneusz, Pepinski Witold, Wolanska-Nowak Paulina, Maciejewska Agnieszka, Paszkowska Regina, Abreu-Glowacka Monica, Achrem Wojciech, Jonkisz Anna, Lebioda Arleta, Konarzewska Magdalena, Ploski Rafal
Department of Criminalistics and Forensic Medicine, University of Warmia and Mazury, Olsztyn, Poland.
Department of Forensic Medicine, Medical University of Bialystok, Poland.
Forensic Sci Int Genet. 2014 Mar;9:142-9. doi: 10.1016/j.fsigen.2013.12.002. Epub 2013 Dec 13.
The objective of the research was to provide a comprehensive database of autosomal microsatellite loci included in AmpFlSTR NGM PCR kit for a population of Poland considering possible genetic differentiation of a forensic interest. Fifteen STR markers were analyzed in 2041 unrelated individuals residing in eight geographically different regions. All the loci were found to be in Hardy-Weinberg equilibrium. The combined probability of match is 3.52 × 10(-19) and the combined Power of Exclusion is 0.9999998. The F(ST) estimate over all 15 STRs is 0.0051 for the Polish population. We established that a combined NGM database may be employed for a Polish population.
该研究的目的是针对波兰人群,考虑到法医鉴定感兴趣的可能遗传分化情况,提供包含在AmpFlSTR NGM PCR试剂盒中的常染色体微卫星基因座的综合数据库。在居住于八个地理区域不同的2041名无关个体中分析了15个STR标记。所有基因座均处于哈迪-温伯格平衡状态。匹配的联合概率为3.52×10(-19),联合排除能力为0.9999998。对于波兰人群,所有15个STR的F(ST)估计值为0.0051。我们确定,合并的NGM数据库可用于波兰人群。