Mwanakasale Victor, Songolo Peter, Babaniyi Olusegun, Simarro Pere
Copperbelt University, School of Medicine, Ndola, Zambia.
J Med Case Rep. 2014 Feb 14;8:53. doi: 10.1186/1752-1947-8-53.
Trypanosoma brucei rhodesiense typically causes acute and severe human African trypanosomiasis in Zambia and other countries in Eastern and Southern Africa. Although a few atypical cases of chronic and mild forms of this disease were reported in Zambia more than 40 years ago, no such cases have been diagnosed over the last four decades.
For the first case, a 19-year-old Black African woman from the Eastern Province of Zambia presented with symptoms and signs of an atypical chronic and mild form of the disease for a period of 2 years. For the second case, a 16-year-old Black African boy from the Northern Province presented with symptoms and signs of a typical acute and severe form of the disease for 3 weeks.
Two strains of T. b. rhodesiense with varying degrees of virulence still do exist in Zambia. This has implications for control strategies at the national level.
罗德西亚布氏锥虫通常在赞比亚以及东部和南部非洲的其他国家引发急性和严重的人类非洲锥虫病。尽管40多年前在赞比亚报告过几例这种疾病的慢性和轻度非典型病例，但在过去的四十年里没有诊断出此类病例。
第一例，一名来自赞比亚东部省的19岁非洲黑人女性，出现非典型慢性和轻度疾病症状及体征达2年。第二例，一名来自北部省的16岁非洲黑人男孩，出现典型急性和严重疾病症状及体征达3周。
赞比亚仍然存在两株毒力不同的罗德西亚布氏锥虫。这对国家层面的控制策略具有影响。
