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[Atherogenic index of plasma in patients with preeclampsia and in healthy pregnant women].

作者信息

Aragon-Charris Jhoan, Reyna-Villasmil Eduardo, Guerra-Velasquez Mery, Mejia-Montilla Jorly, Torres-Cepeda Duly, Santos-Bolívar Joel, Reyna-Villasmil Nadia

机构信息

Servicio de Ginecología y Obstetricia, Hospital Central Dr. Urquinaona, Maracaibo, Estado Zulia, Venezuela.

Servicio de Ginecología y Obstetricia, Hospital Central Dr. Urquinaona, Maracaibo, Estado Zulia, Venezuela.

出版信息

Med Clin (Barc). 2014 Aug 4;143(3):104-8. doi: 10.1016/j.medcli.2013.05.037. Epub 2014 Feb 13.

DOI:10.1016/j.medcli.2013.05.037
PMID:24529401
Abstract

BACKGROUND AND OBJECTIVE

To compare the values of the atherogenic index of plasma between preeclamptic patients and healthy pregnant women.

PATIENTS AND METHOD

Seventy patients were selected. Twenty-three severe preeclamptic patients (group A), 12 mild preeclamptic patients (group B) and 35 healthy pregnant women with similar age and body mass index (group C). Blood samples for lipids and lipoproteins determination were taken and the atherogenic plasma index was calculated.

RESULTS

We did not find differences in group A and B with regard to maternal age, gestational age at the time of evaluation and body mass index compared with pregnant women in group C (P=ns). Plasma concentrations of triglycerides and low-density lipoproteins were significantly higher in patients of groups A and B compared with group C (P<.05). Normotensive patients presented higher concentrations of high-density lipoproteins than patients with severe and mild preeclampsia (P<.05). There were no differences between groups in plasma cholesterol concentrations (P=ns). Patients in groups A (1.14±0.44) and in group B (0.95±0.46) presented significantly higher values of the atherogenic index of plasma compared with pregnant women in group C (0.62±0.20; P<.05).

CONCLUSION

Patients with preeclampsia had higher values of the atherogenic index of plasma than healthy pregnant women.

摘要

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