Suppr超能文献

一组法国克罗恩病患者的诊断延迟情况。

Diagnostic delay in a French cohort of Crohn's disease patients.

作者信息

Nahon Stéphane, Lahmek Pierre, Lesgourgues Bruno, Poupardin Cécile, Chaussade Stanislas, Peyrin-Biroulet Laurent, Abitbol Vered

机构信息

Division of Gastroenterology and Hepatology, GHI Le Raincy-Montfermeil, Montfermeil, France.

Hopital Emile Roux, Limeil-Brevannes, France.

出版信息

J Crohns Colitis. 2014 Sep;8(9):964-9. doi: 10.1016/j.crohns.2014.01.023. Epub 2014 Feb 13.

Abstract

UNLABELLED

Diagnostic delay is frequent in Crohn's disease (CD) and may partly depend on socioeconomic status. The aim of this study was to determine the diagnostic delay and to identify associated risk factors, including socioeconomic deprivation in a French cohort of CD patients.

METHODS

Medical and socioeconomic characteristics of all consecutive CD patients followed in 2 referral centers between September 2002 and July 2012 were prospectively recorded using an electronic database. Diagnostic delay was defined as the time period (months) from the first symptom onset to CD diagnosis. A long diagnostic delay was defined by the upper quartile of this time period. Univariate and multivariate analyses were performed to identify the baseline characteristics of patients associated with a long diagnostic delay.

RESULTS

Three hundred and sixty-four patients with CD (mean age=29.2±12.6 years, 40.8% men) were analyzed. Median diagnostic delay was 5 months, and a long diagnostic delay was more than 12 months. Fifty-six patients (15.3%) had perianal lesions, and 28 patients (8.6%) had complicated disease at diagnosis. None of the following factors were associated with a long diagnostic delay: age, gender, CD location and behavior, marital and educational, language understanding, geographic origin and socioeconomic deprivation score measured by the EPICES score.

CONCLUSION

In this French referral center-based cohort of CD patients, the median diagnostic delay was 5 months. None of the baseline characteristics of the CD, including socioeconomic deprivation, influenced diagnostic delay in this cohort.

摘要

未标注

克罗恩病(CD)的诊断延迟很常见,且可能部分取决于社会经济地位。本研究的目的是确定诊断延迟情况,并识别相关危险因素,包括法国一组CD患者中的社会经济剥夺情况。

方法

2002年9月至2012年7月期间在2个转诊中心接受随访的所有连续CD患者的医学和社会经济特征,通过电子数据库进行前瞻性记录。诊断延迟定义为从首次症状出现到CD诊断的时间段(月)。长诊断延迟定义为此时间段的上四分位数。进行单因素和多因素分析以识别与长诊断延迟相关的患者基线特征。

结果

分析了364例CD患者(平均年龄 = 29.2±12.6岁,男性占40.8%)。中位诊断延迟为5个月,长诊断延迟超过12个月。56例患者(15.3%)有肛周病变,28例患者(8.6%)在诊断时有复杂疾病。以下因素均与长诊断延迟无关:年龄、性别、CD部位和行为、婚姻和教育程度、语言理解能力、地理来源以及通过EPICES评分衡量的社会经济剥夺得分。

结论

在这个以法国转诊中心为基础的CD患者队列中,中位诊断延迟为5个月。CD的基线特征,包括社会经济剥夺,均未影响该队列中的诊断延迟。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验