Saghatchian Mahasti, Bihan Céline, Chenailler Catherine, Mazouni Chafika, Dauchy Sarah, Delaloge Suzette
Institut Gustave Roussy, Department of Medical Oncology, Villejuif, France.
Institut Gustave Roussy, Department of Medical Oncology, Villejuif, France.
Breast. 2014 Jun;23(3):279-85. doi: 10.1016/j.breast.2014.01.009. Epub 2014 Feb 13.
Complementary and alternative medicine (CAM) is increasingly popular among cancer patients but can interfere with conventional therapies; timely data are needed to adapt current patients' care.
This transversal, prospective study evaluated the use of CAM among patients receiving adjuvant chemotherapy or endocrine therapy for early stage breast cancer. We assessed the prevalence of use, the motivations and predictive factors for use, as well as patients' information needs over a three months period.
69/184 responders (37.5%) reported using at least one CAM. CAM use was associated with younger age (p = 0.03) and higher education level (p < 0.001). Pharmacological substances (e.g., homeopathy, phytotherapy) were the most commonly used (79.7%) before physical means (42%) and dietary methods (31.9%). A total of 65.8% of users felt that these treatments have demonstrated evidence of efficacy and 74.8% that they were not associated with side effects. The main goal for use was improvement of treatment-related symptoms (28.3%); secondary goal was increasing the general health status (20.5%). Patients reported high needs for information on CAMs. CAM use was associated with mild differences in secondary adverse events reported by patients.
Breast cancer patients are common users of CAM concomitantly to their conventional cancer treatments and should be investigated regarding their current consumption of CAM. Furthermore, they need advice evidence-based data on these treatments and potential interactions with on-going treatments.
补充和替代医学（CAM）在癌症患者中越来越受欢迎，但可能会干扰传统疗法；需要及时获取数据以调整当前患者的治疗方案。
这项横断面前瞻性研究评估了早期乳腺癌患者在接受辅助化疗或内分泌治疗期间使用补充和替代医学的情况。我们在三个月的时间里评估了其使用 prevalence、使用动机和预测因素，以及患者的信息需求。
69/184 名应答者（37.5%）报告使用了至少一种补充和替代医学。补充和替代医学的使用与较年轻的年龄（p = 0.03）和较高的教育水平（p < 0.001）相关。药物类物质（如顺势疗法、植物疗法）是最常用的（79.7%），其次是物理方法（42%）和饮食方法（31.9%）。共有 65.8%的使用者认为这些治疗已证明有效，74.8%的使用者认为它们无副作用。使用的主要目的是改善与治疗相关的症状（28.3%）；次要目的是提高总体健康状况（20.5%）。患者报告对补充和替代医学信息有很高的需求。补充和替代医学的使用与患者报告的次要不良事件的轻微差异相关。
乳腺癌患者在接受传统癌症治疗的同时普遍使用补充和替代医学，应调查他们目前对补充和替代医学的使用情况。此外，他们需要基于证据的关于这些治疗以及与正在进行的治疗潜在相互作用的建议。
