Lee Seung Wha, Cha Sang Hoon, Chung Hwan Hoon, Kim Kee Hwan, Yeom Suk Keu, Seo Bo Kyung, Je Bo Kyung, Kim Baek Hyun
Department of Radiology, Korea University Ansan Hopsital, # 516 GoJan 1-dong, Ansan-si, Gyeonggi-do, Korea, 425-707.
Department of Radiology, Korea University Ansan Hopsital, # 516 GoJan 1-dong, Ansan-si, Gyeonggi-do, Korea, 425-707.
Magn Reson Imaging. 2014 May;32(4):385-91. doi: 10.1016/j.mri.2014.01.003. Epub 2014 Jan 13.
To describe the patterns of bile distribution in the biliary tree, duodenum, jejunum, and stomach, and to determine the gallbladder ejection fraction (GBEF) by using functional magnetic resonance cholangiography (MRC) with gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid (Gd-EOB-DTPA) in healthy volunteers.
Forty subjects were included in this study. After conventional MRC, pre-fatty meal MRC (PRFM) was obtained at 30, 40, 50, and 60min after contrast agent injection. Then, post-fatty meal MRC (POFM) was obtained every 10min for 1h. We assessed the PRFM and POFM for opacification of contrast agent in the first- and second-order intrahepatic ducts (IHDs) and the common bile duct (CBD). Contrast agent opacification in the cystic duct was assessed, and the percentage volume of contrast agent filling in the gallbladder (GB) was calculated on PRFM. We calculated the GBEF and assessed the presence of contrast agent in the GB, duodenum, jejunum, and stomach.
Thirty-six (90%) subjects showed grade 3 CBD opacification (visible contrast and well-defined bile duct border) on 60-min PRFM. Thirty-four (85%) subjects showed grade 3 first-order IHD opacification on 60-min PRFM. All (100%) subjects showed cystic duct opacification of contrast agent, and the average percentage volume of contrast agent filling in the GB was 68.81%±16.84% on 60-min PRFM. The GBEF at 30-min POFM was 35.00%±18.26%. Ten (25%) subjects had no contrast agent in the stomach and small bowel on all PRFMs. Twelve (30%) subjects had contrast medium in the stomach on PRFM and/or POFM.
Functional MRC with Gd-EOB-DTPA can allow determining the distribution of bile in the biliary tree and small intestine, as well as the GBEF.
描述胆管树、十二指肠、空肠和胃内胆汁的分布模式，并通过使用钆塞酸二钠（Gd-EOB-DTPA）的功能磁共振胆管造影（MRC）来测定健康志愿者的胆囊排空分数（GBEF）。
本研究纳入40名受试者。在常规MRC后，于注射造影剂后30、40、50和60分钟获取脂肪餐前MRC（PRFM）。然后，每10分钟获取1小时的脂肪餐后MRC（POFM）。我们评估PRFM和POFM中肝内一、二级胆管（IHDs）和胆总管（CBD）内造影剂的显影情况。评估胆囊管内造影剂的显影情况，并在PRFM上计算胆囊（GB）内造影剂充盈的体积百分比。我们计算GBEF并评估GB、十二指肠、空肠和胃内造影剂的存在情况。
36名（90%）受试者在60分钟PRFM上显示3级CBD显影（可见造影剂且胆管边界清晰）。34名（85%）受试者在60分钟PRFM上显示3级肝内一级胆管显影。所有（100%）受试者均显示胆囊管内造影剂显影，在60分钟PRFM上，胆囊内造影剂充盈的平均体积百分比为68.81%±16.84%。30分钟POFM时的GBEF为35.00%±18.26%。10名（25%）受试者在所有PRFM上胃和小肠内均无造影剂。12名（30%）受试者在PRFM和/或POFM上胃内有造影剂。
使用Gd-EOB-DTPA的功能MRC能够确定胆汁在胆管树和小肠中的分布以及GBEF。
