Shade Marcia Y, Berger Ann M, Chaperon Claudia
Res Gerontol Nurs. 2014 Jul-Aug;7(4):178-92. doi: 10.3928/19404921-20140210-01. Epub 2014 Feb 19.
Potentially inappropriate medication (PIM) use is a significant worldwide public health problem. Community-dwelling older adults are susceptible to the negative outcomes associated with the use of PIMs. A database search (January 1991-June 2013) produced 19 prospective correlational and 10 intervention studies. The current state of the science reveals that conceptual clarity is lacking regarding the use of PIMs. The prevalence of PIM use is well documented in an abundance of descriptive studies. However, researchers have not examined an intervention's effects on health outcomes in community-dwelling older adults. Although independent older adults can acquire PIMs outside of a provider, current interventions aim to change the behavior of the prescribing physician and pharmacist. Nurses need to collaborate with other disciplines in PIM use research. Priority needs are to design interventions that reduce the use of PIMs and negative health outcomes.
潜在不适当用药（PIM）的使用是一个全球性的重大公共卫生问题。社区居住的老年人容易受到与使用PIM相关的负面后果的影响。一项数据库检索（1991年1月至2013年6月）产生了19项前瞻性相关性研究和10项干预性研究。目前的科学状况表明，在PIM的使用方面缺乏概念清晰度。大量描述性研究充分记录了PIM的使用流行情况。然而，研究人员尚未考察干预措施对社区居住老年人健康结局的影响。虽然独立的老年人可以在医疗机构之外获取PIM，但目前的干预措施旨在改变开处方的医生和药剂师的行为。护士需要在PIM使用研究中与其他学科合作。当务之急是设计减少PIM使用和负面健康结局的干预措施。
