Vidal N A, Arranz C T, Mones Sias M C, Herrmann A P, Martinez Seeber A
Biología General and Fisiología Humana, Facultad de Farmacia y Bioquímica, Buenos Aires, Argentina.
Arch Int Physiol Biochim. 1987 Nov;95(4):329-32.
In the rat, the effects of an atrial natriuretic factor (ANF) (Rat, 8-33 Peninsula Lab) on body water distribution have been evaluated. The ANF administration to nephrectomized animals produced a decrease in plasma volume and a slight increase in haematocrit and in plasma albumin concentration. No modifications were observed in total and intracellular water. The fluid efflux from the capillaries appeared to be located in the interstitial space. These results suggest that ANF could regulate plasma volume and systemic blood pressure, concurrently with its other known effects.
在大鼠中，已评估了心房利钠因子（ANF）（大鼠，8 - 33半岛实验室）对机体水分分布的影响。给肾切除动物注射ANF会导致血浆量减少，血细胞比容和血浆白蛋白浓度略有增加。总水量和细胞内水量未观察到变化。毛细血管的液体流出似乎位于间质空间。这些结果表明，ANF在发挥其其他已知作用的同时，可能还能调节血浆量和全身血压。
