Jamaati Hamid Reza, Shadmehr Mohammad Behgam, Aloosh Oldouz, Radmand Golnar, Mohajerani Seyed Amir, Hashemian Seyed Mohammadreza
Chronic Respiratory Disease Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Asian Cardiovasc Thorac Ann. 2013 Apr;21(2):181-6. doi: 10.1177/0218492312454537.
Post-intubation tracheal stenosis is a serious disease caused by cuff pressure during tracheal intubation. The reported prevalence of post-intubation tracheal stenosis is 10%-22% in intubated patients. Invasive diagnostic methods based on fiberoptic or rigid bronchoscopy are suggested for initial assessment and treatment. This study aimed to evaluate plethysmography as an alternative diagnostic tool for post-intubation tracheal stenosis. We also assessed the relationship between plethysmography and bronchoscopy findings in patients with post-intubation tracheal stenosis.
The sample included 30 patients who were admitted to our intensive care unit or surgical ward during the course of a year, and diagnosed with post-intubation tracheal stenosis. All patients underwent plethysmography and rigid bronchoscopy. The relationship between the plethysmography and bronchoscopy findings was examined.
Stricture intensity had the strongest correlation with upper airway resistance (p = 0.001). The relationship of length of stricture to forced expiratory volume in 1 s and maximum expiratory flow 50 and 75 was significant in univariate analysis, and to reserve volume and total lung capacity in multivariate analysis.
Significant relationships were found between plethysmography variables and rigid bronchoscopy findings in patients with post-intubation tracheal stenosis, and some formulas were developed to give an alternative estimate of stricture severity, without bronchoscopy.
气管插管后气管狭窄是气管插管期间袖带压力导致的一种严重疾病。据报道,气管插管患者中气管插管后气管狭窄的患病率为10% - 22%。建议采用基于纤维支气管镜或硬质支气管镜的侵入性诊断方法进行初步评估和治疗。本研究旨在评估体积描记法作为气管插管后气管狭窄的一种替代诊断工具。我们还评估了气管插管后气管狭窄患者体积描记法与支气管镜检查结果之间的关系。
样本包括在一年期间入住我们重症监护病房或外科病房并被诊断为气管插管后气管狭窄的30例患者。所有患者均接受了体积描记法和硬质支气管镜检查。检查了体积描记法与支气管镜检查结果之间的关系。
狭窄强度与上气道阻力的相关性最强(p = 0.001)。在单因素分析中,狭窄长度与1秒用力呼气量、最大呼气流量50和75之间的关系显著,在多因素分析中与残气量和肺总量之间的关系显著。
在气管插管后气管狭窄患者中,体积描记法变量与硬质支气管镜检查结果之间存在显著关系,并且开发了一些公式,在不进行支气管镜检查的情况下对狭窄严重程度进行替代估计。