Vijayakumar Mahalingam, Nageswaran Prahlad, Tirukalathi O Manimegalai, Sudha Ekambaram, Priyadarshini Shweta
Department of Pediatric Nephrology and Pediatrics, Mehta Children's Hospital, Chennai, Tamilnadu, India.
Int J Nephrol Renovasc Dis. 2014 Feb 7;7:69-73. doi: 10.2147/IJNRD.S53541. eCollection 2014.
Clinical, biochemical, and ultrasonographic findings in 91 consecutive children presenting with hypercalciuria were analyzed along with the results of treatment to determine the clinical profile of hypercalciuria and its outcome. Hypercalciuria was common in children aged 1-5 years (39.6%), and hematuria was the most frequent symptom. There was no significant difference between 24-hour urinary calcium and random urinary calcium/creatinine ratio values between males and females. The random urinary calcium/creatinine ratio was found to be useful for screening and also for documenting the benefit of therapy. The children were essentially treated with thiazides, and the majority showed a good response, with a good overall outcome on follow-up.
对91例连续出现高钙尿症的儿童的临床、生化及超声检查结果进行了分析，并结合治疗结果来确定高钙尿症的临床特征及其预后。高钙尿症在1至5岁儿童中很常见（39.6%），血尿是最常见的症状。男性和女性的24小时尿钙及随机尿钙/肌酐比值之间无显著差异。随机尿钙/肌酐比值被发现对筛查以及记录治疗效果很有用。这些儿童主要接受噻嗪类药物治疗，大多数反应良好，随访时总体预后良好。
