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[实体肿瘤治疗中的新型放射技术。转移瘤的放射治疗]

[Novel irradiation techniques in the treatment of solid tumours. Radiotherapy for metastases].

作者信息

Mayer Arpád, Póti Zsuzsa

机构信息

Uzsoki utcai Kórház Fővárosi Onkoradiológiai Központ Budapest Uzsoki u. 29. 1145.

出版信息

Orv Hetil. 2014 Feb 23;155(8):283-90. doi: 10.1556/OH.2014.29832.

Abstract

Novel developments in percutaneous radiotherapy, such as positron emission tomography/computed tomography, adaptive radiation planning, intensity modulation radiotherapy and intensity modulated arc therapy (RapidArc), as well as the newer generation of image control (cone-beam computed tomography) and image guided radiotherapy ensure increased dosages of planning target volume and clinical target volume of solid tumours without damaging surrounding tissues and providing maximal protection. By raising the dosages of planned target volume and clinical target volume, these novel technical developments have created new indications in the treatment of solid tumours. With the aid of the cone-beam computed tomography and image guided radiotherapy the organ metastasis (lung, liver, spinal cord) and the primary tumour can be treated safety and effectively. Hypofractionation, dose escalation and the use of stereotactic devices can probably decrease radiation damage. The authors review the most common forms of evidence-based fractionation schemes used in irradiation therapy.

摘要

经皮放射治疗的新进展,如正电子发射断层扫描/计算机断层扫描、自适应放射治疗计划、调强放射治疗和容积调强弧形治疗(速锋刀),以及新一代图像控制(锥形束计算机断层扫描)和图像引导放射治疗,确保了实体瘤计划靶区和临床靶区剂量增加,同时不损伤周围组织并提供最大程度的保护。通过提高计划靶区和临床靶区的剂量,这些新的技术进展为实体瘤的治疗创造了新的适应症。借助锥形束计算机断层扫描和图像引导放射治疗,可安全有效地治疗器官转移瘤(肺、肝、脊髓)和原发性肿瘤。大分割放疗、剂量递增和立体定向装置的使用可能会减少放射损伤。作者回顾了放射治疗中最常见的循证分割方案形式。

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