Nakao Jolene H, Wiener Dan E, Newman David H, Sharp Victoria L, Egan Daniel J
Department of Emergency Medicine, St. Luke's Roosevelt Hospital, New York, NY, USA.
David H. Newman, Department of Emergency Medicine, Mount Sinai School of Medicine, New York, NY, USA.
Int J STD AIDS. 2014 Oct;25(12):887-93. doi: 10.1177/0956462414523944. Epub 2014 Feb 17.
Summary Newly diagnosed HIV-positive patients have frequent health care encounters prior to diagnosis representing missed opportunities for diagnosis. This study determines the proportion of patients with new HIV diagnoses with encounters in the 3 years prior to diagnosis. We describe the characteristics of newly diagnosed patients and of "late testers" (CD4 <200 cells/mm(3) at the time of diagnosis). We identified all newly diagnosed with HIV in emergency department, inpatient, and outpatient settings between May 1, 2006, and December 31, 2009. Data abstractors searched hospital records to identify all emergency department, inpatient, and outpatient visits for the 3 years prior to diagnosis. In all, 23,271 HIV tests were performed and 253 persons were newly diagnosed (1.1%); 152 new positives (60.1%) made at least one prior visit. Of patients with CD4 counts available, 104/175 (59.4%) had CD4 <200 cells/mm(3). Patients with at least one prior visit had a median of three. There was no difference in numbers of visits between late testers and non-late testers, although late testers were more likely to have ED visits. Most newly diagnosed HIV-positive patients had multiple encounters prior to diagnosis. Many of these patients presented with CD4 counts below 200 cells/mm(3), indicating true missed opportunities for earlier diagnosis.
新诊断出的HIV阳性患者在确诊前经常接受医疗保健服务,这代表着诊断的错失良机。本研究确定了在诊断前3年内有就诊经历的新诊断出HIV患者的比例。我们描述了新诊断患者以及“晚期检测者”(诊断时CD4细胞计数<200个/立方毫米)的特征。我们确定了2006年5月1日至2009年12月31日期间在急诊科、住院部和门诊部新诊断出HIV的所有患者。数据提取人员查阅医院记录,以确定诊断前3年的所有急诊科、住院部和门诊部就诊情况。总共进行了23271次HIV检测,253人被新诊断出感染HIV(1.1%);152例新确诊患者(60.1%)此前至少有过一次就诊。在有CD4细胞计数数据的患者中,104/175(59.4%)的CD4细胞计数<200个/立方毫米。至少有过一次就诊的患者中位数为三次就诊。晚期检测者和非晚期检测者的就诊次数没有差异,不过晚期检测者更有可能在急诊科就诊。大多数新诊断出的HIV阳性患者在确诊前有多次就诊经历。这些患者中有许多人的CD4细胞计数低于200个/立方毫米,这表明确实存在早期诊断的错失良机。