Areshev G P, Agapov A A, Gratsianskiĭ N A, Ananich V A
Kardiologiia. 1988 Feb;28(2):34-7.
A total of 130 patients with angina of new onset were examined within first 3 months of the disease. Macrofocal myocardial infarction survivors were not admitted to the study. The investigation included selective coronaro-angiography and ventriculography, Holter's ECG monitoring over 24 to 48 hours and bicycle ergometry. Programmed right-ventricular electric stimulation was conducted in 41 patients. Only one major coronary artery was affected in 78% of patients. Left-ventricular ejection fraction nearly always exceeded 50%. Groups of ventricular extrasystoles were detected by ECG monitoring in 10.8% and by bicycle ergometry in 2.5%. No signs of electrical instability were ever detected at programmed stimulation, done in the absence of anginal attacks. Groups of ventricular extrasystoles were more common, as compared to single extrasystoles (p less than 0.001), in acute myocardial ischemia, being more frequently associated with unstable rather than stable angina of new onset (p less than 0.05). In early coronary heart disease, signs of electric ventricular instability are not detectable in the absence of myocardial ischemia.
共有130例初发心绞痛患者在发病后的前3个月内接受了检查。大面积心肌梗死幸存者未纳入本研究。检查项目包括选择性冠状动脉造影和心室造影、24至48小时的动态心电图监测以及自行车运动试验。对41例患者进行了程控右心室电刺激。78%的患者仅累及一支主要冠状动脉。左心室射血分数几乎总是超过50%。通过心电图监测在10.8%的患者中检测到室性早搏组，通过自行车运动试验在2.5%的患者中检测到室性早搏组。在无心绞痛发作时进行的程控刺激中，从未检测到电不稳定迹象。与单个早搏相比，室性早搏组在急性心肌缺血时更为常见（p<0.001），且更常与初发不稳定型而非稳定型心绞痛相关（p<0.05）。在早期冠心病中，在无心肌缺血的情况下无法检测到心室电不稳定迹象。
