孕期接触甲巯咪唑后并发皮肤发育不全时甲胎蛋白升高
Elevated alpha-fetoprotein in pregnancy complicated by aplasia cutis after exposure to methimazole.
作者信息
Farine D, Maidman J, Rubin S, Chao S
机构信息
Department of Obstetrics and Gynecology, Columbia Presbyterian Medical Center, New York, New York.
出版信息
Obstet Gynecol. 1988 Jun;71(6 Pt 2):996-7.
PMID:2453822
Abstract
A case of aplasia cutis after exposure to methimazole (Tapazole) in early pregnancy is described. Elevated maternal serum alpha-fetoprotein (MSAFP) and amniotic fluid alpha-fetoprotein (AFP) were found. Elevated MSAFP and amniotic fluid AFP in women exposed to methimazole may suggest this rare fetal condition.
摘要
本文描述了一例在孕早期接触甲巯咪唑（他巴唑）后发生皮肤发育不全的病例。发现母体血清甲胎蛋白（MSAFP）和羊水甲胎蛋白（AFP）升高。接触甲巯咪唑的女性中MSAFP和羊水AFP升高可能提示这种罕见的胎儿疾病。
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