Jakobsen H, Torp-Pedersen S, Juul N
Department of Urology, Herlev Hospital, University of Copenhagen, Denmark.
Scand J Urol Nephrol Suppl. 1988;107:26-31.
In 175 normal men aged 27-70 (median 40) years, the prostate was ultrasonically scanned by the transrectal route. Ultrasonic signs of adenoma were found in 26%. The earliest age at which signs of benign prostatic hyperplasia appeared was 27 years, and the incidence increased with age. Adenomatous prostates were significantly larger than nonadenomatous, with median volume 28.0 (14.5-62.1) ml versus 23.0 (11.3-39.1) ml (p less than 0.0005). The adenomatous prostates also had a larger median volume of the periurethral gland (4.1 ml vs. 3.0 ml; p less than 0.0005) and a larger peripheral zone (23.3 ml vs. 20.2 ml; p less than 0.005). The total prostatic volume increased statistically significantly with age and the growth rate was calculated to be 0.81 %/year +/- 0.25 (S.E.) corresponding to 0.2 ml/year. The growth rate of the periurethral zone was 1.5 %/year +/- 0.5 (S.E.). Volumetric correlation between periurethral gland and total prostatic volume depended on whether or not adenoma had developed. Prostatic volumes measured in vivo by ultrasound are slightly greater than values obtained at autopsy.
对175名年龄在27至70岁（中位数40岁）的正常男性经直肠途径进行前列腺超声扫描。发现26%的人有腺瘤的超声征象。良性前列腺增生征象最早出现的年龄为27岁，且发病率随年龄增加。腺瘤性前列腺明显大于非腺瘤性前列腺，中位数体积分别为28.0（14.5 - 62.1）ml和23.0（11.3 - 39.1）ml（p < 0.0005）。腺瘤性前列腺的尿道周围腺体中位数体积也更大（4.1 ml对3.0 ml；p < 0.0005），外周带也更大（23.3 ml对20.2 ml；p < 0.005）。前列腺总体积随年龄增长有统计学显著增加，计算得出增长率为每年0.81%±0.25（标准误），相当于每年0.2 ml。尿道周围区的增长率为每年1.5%±0.5（标准误）。尿道周围腺体与前列腺总体积的体积相关性取决于是否已发生腺瘤。超声在体内测量的前列腺体积略大于尸检获得的值。
