Tanaka Kota, Hitosugi Masahito, Takaso Marin, Nakamura Mami, Takeda Arisa
Department of Legal Medicine, Shiga University of Medical Science, Otsu 520-2192, Japan.
Healthcare (Basel). 2023 May 19;11(10):1486. doi: 10.3390/healthcare11101486.
Because decedents undergoing forensic autopsies would have behaved normally before death, prostate volume according to age group can be confirmed with forensic autopsy materials. The objectives of this study were to first confirm the current prostate volume by age and then determine diseases that can influence prostate volume using forensic autopsy materials. Prostate specimens were collected from forensic autopsies performed at Shiga University of Medical Science, Japan, between January 2015 and December 2019. Overall, 207 decedents were included in the study. Prostate volume was measured by the Archimedes' principle. Concomitant diseases were determined by the past medical histories and autopsy results. The mean crude prostate volume was 29.1 ± 10.3 mL (range, 2.8-88.0 mL). The crude prostate volume increased with age. The mean corrected prostate volume (divided by body surface area) was significantly higher in patients with atherosclerosis than in those without. However, multiple regression analysis revealed that only age influenced the corrected prostate volume. Age was the only significant influencing factor for prostate volume. We propose applying age estimation using prostate volume for forensic medicine purposes. Because prostate volume was not influenced by concomitant disease, it would be valuable to estimate the decedent's age using the prostate volume.
由于接受法医尸检的死者在死亡前行为正常，因此可以通过法医尸检材料确定各年龄组的前列腺体积。本研究的目的首先是按年龄确认当前的前列腺体积，然后使用法医尸检材料确定可能影响前列腺体积的疾病。前列腺标本取自2015年1月至2019年12月在日本滋贺医科大学进行的法医尸检。总体而言，207名死者纳入了本研究。前列腺体积通过阿基米德原理测量。伴随疾病根据既往病史和尸检结果确定。前列腺平均原始体积为29.1±10.3 mL（范围为2.8 - 88.0 mL）。原始前列腺体积随年龄增长而增加。动脉粥样硬化患者的平均校正前列腺体积（除以体表面积）显著高于无动脉粥样硬化的患者。然而，多元回归分析显示只有年龄影响校正前列腺体积。年龄是前列腺体积唯一的显著影响因素。我们建议将基于前列腺体积的年龄估计应用于法医学目的。由于前列腺体积不受伴随疾病影响，利用前列腺体积估计死者年龄将很有价值。
