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Two new mutants, 'trembler' and 'reeler', with neurological actions in the house mouse (Mus musculus L.).

作者信息

FALCONER D S

出版信息

J Genet. 1951 Jan;50(2):192-201. doi: 10.1007/BF02996215.

DOI:10.1007/BF02996215
PMID:24539699
Abstract
摘要

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1
Two new mutants, 'trembler' and 'reeler', with neurological actions in the house mouse (Mus musculus L.).家鼠(小家鼠)中具有神经学效应的两个新突变体,“颤抖者”和“旋转者”。
J Genet. 1951 Jan;50(2):192-201. doi: 10.1007/BF02996215.
2
Neurological actions caused by the mutant gene Trembler in the house mouse (Mus musculus, L.,) an investigation.家鼠(小家鼠,L.)中由突变基因“颤抖者”引起的神经学作用的一项研究。
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Mutations induced in Coprinus fimetarius (L) by nitrogen mustard.氮芥诱导粪生鬼伞产生的突变
Nature. 1948 Nov 27;162(4126):846. doi: 10.1038/162846a0.
2
Heterocaryosis in Neurospora Crassa.粗糙脉孢菌中的异核现象。
Genetics. 1944 May;29(3):291-308. doi: 10.1093/genetics/29.3.291.
Reelin标记可卡因激活的纹状体神经元,促进神经元兴奋性,并调节可卡因奖赏。
Sci Adv. 2025 Mar 28;11(13):eads4441. doi: 10.1126/sciadv.ads4441. Epub 2025 Mar 26.
4
Genetic or therapeutic disruption of the Reelin/Apoer2 signaling pathway improves inflammatory arthritis outcomes.Reelin/Apoer2信号通路的基因或治疗性破坏可改善炎性关节炎的预后。
Proc Natl Acad Sci U S A. 2025 Mar 18;122(11):e2418642122. doi: 10.1073/pnas.2418642122. Epub 2025 Mar 12.
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Cerebellar nuclei cells produce distinct pathogenic spike signatures in mouse models of ataxia, dystonia, and tremor.小脑核细胞在共济失调、肌张力障碍和震颤的小鼠模型中产生独特的致病棘波特征。
Elife. 2024 Jul 29;12:RP91483. doi: 10.7554/eLife.91483.
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De novo monoallelic Reelin missense variants cause dominant neuronal migration disorders via a dominant-negative mechanism.从头发生的 Reelin 单等位基因突变导致显性神经元迁移障碍,其机制为显性负性。
J Clin Invest. 2024 Jul 9;134(16):e153097. doi: 10.1172/JCI153097.
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Safety of Anti-Reelin Therapeutic Approaches for Chronic Inflammatory Diseases.抗 Reelin 治疗策略治疗慢性炎症性疾病的安全性。
Cells. 2024 Mar 27;13(7):583. doi: 10.3390/cells13070583.
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Molecular Mechanisms of Reelin in the Enteric Nervous System and the Microbiota-Gut-Brain Axis: Implications for Depression and Antidepressant Therapy.瑞林在肠神经系统和微生物群-肠-脑轴中的分子机制:对抑郁症和抗抑郁治疗的影响。
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Cerebellar dysfunction in rodent models with dystonia, tremor, and ataxia.患有肌张力障碍、震颤和共济失调的啮齿动物模型中的小脑功能障碍。
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The genetics of gaits in Icelandic horses goes beyond DMRT3, with RELN and STAU2 identified as two new candidate genes.冰岛马步态的遗传学不仅与 DMRT3 有关,还发现 RELN 和 STAU2 是两个新的候选基因。
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