[鼠神经母细胞瘤细胞对河豚毒素敏感的细胞质蛋白的抗体吸附作用]
[Antibody adsorption to tetrodotoxin-sensitive cytoplasmic proteins by murine neuroblastoma cells].
作者信息
Pinchuk G V, Pinchuk L N, Gerasimenko O V
出版信息
Neirofiziologiia. 1988;20(1):98-105.
PMID:2454412
Abstract
The study was aimed to examine properties of polyclonal antibodies elicited after immunization by cytoplasmic nerve cell glycoproteins forming sodium channels in liposomes. It was shown that intact murine neuroblastoma cells can absorb these antibodies. Absorbing cell dose-effect curves were found to have a characteristic form able to shift when the cell culture time or serum concentration in the growth medium varied.
摘要
该研究旨在检测由脂质体中形成钠通道的细胞质神经细胞糖蛋白免疫后引发的多克隆抗体的特性。结果表明，完整的小鼠神经母细胞瘤细胞能够吸收这些抗体。当细胞培养时间或生长培养基中的血清浓度变化时，发现吸收细胞剂量效应曲线具有能够移动的特征形式。
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