Hallissey M T, Allum W H, Roginski C, Fielding J W
Department of Surgery, Queen Elizabeth Hospital, Birmingham, England.
Cancer. 1988 Jul 15;62(2):440-4. doi: 10.1002/1097-0142(19880715)62:2<440::aid-cncr2820620232>3.0.co;2-n.
Most patients with gastric carcinoma have a disease that is too advanced for radical surgery. A Review was made of 13,175 cases of gastric carcinoma registered at the Birmingham Cancer Registry during the period of 1960-1969. Of the patients, 79.6% had disease that was not radically resected, and few of these patients survived to 2 years. Those who had a palliative resection or bypass had the lowest 30-day mortality rate when compared to all other palliative measures (P less than 0.001). Furthermore, palliative resection gave the best survival in the presence of both locally advanced and metastatic disease (P less than 0.001). This suggests that the best palliative procedure for those with a disease unsuitable for radical surgery is a resection.
大多数胃癌患者所患疾病已进展到无法进行根治性手术的程度。对1960年至1969年期间在伯明翰癌症登记处登记的13175例胃癌病例进行了回顾。在这些患者中,79.6%的患者疾病无法进行根治性切除,这些患者中很少有人能存活至2年。与所有其他姑息性措施相比,接受姑息性切除或旁路手术的患者30天死亡率最低(P<0.001)。此外,对于局部晚期和转移性疾病患者,姑息性切除的生存率最高(P<0.001)。这表明,对于不适合进行根治性手术的患者,最佳的姑息性手术是切除。